GMRS implant system

For decades, Stryker has offered modular implant solutions for surgeons who treat patients in need of significant bone reconstruction. We have set the standard for modular implant devices and now more than ever, we’re committed to continuing this legacy of innovation and care.

Stryker’s Global Modular Replacement System® (GMRS) is designed to compensate for bone loss and address joint stability, to help retain the quality of life for patients who require radical bone resection.

Talk to your doctor to see if GMRS is right for you.

Global Modular Replacement System portfolio
Important information

The Global Modular Replacement System (GMRS) is intended for use in patients requiring extensive reconstruction of the hip joint and/or knee joint, including knee fusions, necessitated by extensive bone loss due to trauma, failed previous prosthesis and/or tumor resection.

GMRS is not appropriate for patients with:

  • A condition that may have already resulted in either local or distant spread of a tumor such as pathological fracture, overt infection, inopportune placement of biopsy incision, and rapid disease progression beyond a respectable margin.
  • Certain types of infections or any mental or neuromuscular disorder which would create an unacceptable risk of prosthesis instability, prosthesis fixation failure, complication in postoperative care, or compromised bone stock.

As with any surgery, reconstruction of the hip joint and/or the knee joint has serious risks which include, but are not limited to, pain, infection, bone fracture, peripheral neuropathies (nerve damage), circulatory compromise (including deep vein thrombosis (blood clots in the legs), genitourinary disorders (including kidney failure), gastrointestinal disorders (including paralytic ileus (loss of intestinal digestive movement)), vascular disorders including thrombus (blood clots), blood loss, or changes in blood pressure or heart rhythm, bronchopulmonary disorders (including emboli, stroke or pneumonia), heart attack, and death.

Implant related risks which may lead to revision include dislocation, subluxation, loosening, fracture, nerve palsy, subclinical nerve damage, soft tissue imbalance, osteolysis, intravascular extension of the tumor, metal sensitivity reactions, and/or accelerated wear of the prosthetic implants. Global Modular Replacement System implants may not provide the same feel or performance characteristics experienced with a normal healthy joint.

The information presented is for educational purposes only. Speak to your doctor to decide if hip and/or knee joint reconstruction surgery is right for you. Individual results vary and not all patients will return to the same postoperative activity level. The lifetime of any joint replacement is limited and varies with each individual. Your doctor will counsel you about how to best maintain your activities in order to potentially prolong the lifetime of the device. Such strategies include not engaging in high-impact activities, such as running, as well as maintaining a healthy weight. It is important to closely follow your doctor’s instructions regarding post-surgery activity, treatment and follow-up care. Ask your doctor if hip and/or knee joint reconstruction is right for you.

Stryker Corporation or its other divisions or other corporate affiliated entities own, use or have applied for the following trademarks or service marks: GMRS, Stryker. All other trademarks are trademarks of their respective owners or holders.


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